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CS-W001157 4
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tert-Butyl (2-aminoethyl)carbamate hydrochloride

  • CAS No. 79513-35-2

  • Cat. No. CS-W015688
  • Purity≥97%
  • MDL No.MFCD01076129

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (2-aminoethyl)carbamate hydrochloride|CS-W015688

Structure of 79513-35-2

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General Information

  • CAS No. 79513-35-2
  • Cat. No. CS-W015688
  • Purity ≥97%
  • MDL No. MFCD01076129
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₇ClN₂O₂
  • Molecular Weight 196.68
  • Synonym(s) N-tert-Butoxycarbonyl-1,2-diaminoethane hydrochloride~tert-Butyl N-(2-aminoethyl)carbamate hydrochloride
  • SMILES O=C(OC(C)(C)C)NCCN.[H]Cl

Description

tert-Butyl (2-aminoethyl)carbamate hydrochloride delivers a protected amine handle for peptide synthesis and chemical biology applications. This bench-stable derivative features a readily cleavable carbamate group, enabling efficient deprotection under mild acidic conditions while maintaining compatibility with diverse reaction environments.

Application

tert-Butyl (2-aminoethyl)carbamate hydrochloride serves as a robust, bench-stable protecting group for primary amines, enabling efficient incorporation of aminoethyl functionalities in peptide synthesis and medicinal chemistry. Its tert-butyl carbamate moiety offers orthogonal deprotection under mild acidic conditions, while the hydrochloride salt enhances solubility and handling. The compound facilitates straightforward functionalization in multistep syntheses, particularly in constructing bioactive heterocycles and drug-like scaffolds.

Synthesis

  • Route1

    References

    • Journal of Organic Chemistry, , vol. 64, # 13 p. 4627 - 4634
  • Route2
    • In-stock
      Di-tert-butyl dicarbonate|CS-0017817
      24424-99-5
    • null|null
      333-18-6
    • ~84%
    • In-stock
      tert-Butyl (2-aminoethyl)carbamate hydrochloride|CS-W015688
      79513-35-2

    References

    • Liebigs Annalen der Chemie, , # 9 p. 941 - 946
  • Route3

    References

    • Synthesis, , p. 366 - 368

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   64.35
  • LogP   0.8916
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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