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Structure of 796090-23-8
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2-Chloro-6-(trifluoromethyl)pyridine-4-carboxylic acid features a strategically positioned trifluoromethyl group enhancing electron-withdrawal and metabolic stability, while the carboxylic acid enables direct conjugation or derivatization. This scaffold integrates seamlessly into bioactive molecule design, offering robustness under standard reaction conditions.
2-Chloro-6-(trifluoromethyl)pyridine-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation into bioactive heterocycles via standard coupling reactions. Its trifluoromethyl and carboxylic acid functionalities provide enhanced metabolic stability and strategic reactivity for Suzuki-Miyaura, Ullmann, or amide bond formation. The molecule exhibits good bench stability and facilitates efficient purification, making it well-suited for high-throughput synthesis and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: