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Structure of 800401-54-1
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6-Chloro-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid features a fused heterocyclic core with a chlorine substituent at the 6-position and a carboxylic acid group at C2, delivering enhanced electron-withdrawing character. This scaffold enables direct incorporation into bioactive molecules, particularly in kinase inhibitors and medicinal chemistry libraries. The compound exhibits good solubility in polar solvents and stability under standard bench conditions, facilitating use in multi-step synthesis workflows.
6-Chloro-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to heterocyclic scaffolds through standard coupling and functionalization reactions. Its well-defined reactivity profile supports direct derivatization at the carboxylic acid group and electrophilic substitution at the C6 position, facilitating rapid analog generation. The compound exhibits good bench stability and compatibility with common protecting group strategies, making it suitable for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: