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Structure of 811450-26-7
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5-Fluoropyrimidin-4-amine features a fluorine atom at the 5-position and an amino group at the 4-position of the pyrimidine ring, creating a potent electron-deficient heterocyclic scaffold. This combination enables direct incorporation into nucleoside analogs and kinase inhibitors, where it enhances binding affinity through dipole interactions and hydrogen bonding. The compound exhibits bench-stable handling characteristics and compatibility with standard coupling protocols in medicinal chemistry workflows.
5-Fluoropyrimidin-4-amine serves as a key heterocyclic building block in medicinal chemistry, enabling efficient access to fluorinated pyrimidine scaffolds. Its reactive amine and electron-deficient ring facilitate nucleophilic substitution, coupling reactions, and derivatization under standard conditions. The compound exhibits bench stability, ease of purification, and compatibility with diverse functional groups, making it a practical reagent for constructing bioactive molecules and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: