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Structure of 81156-68-5
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2,4-Dichlorophenethyl alcohol offers a robust phenethyl scaffold bearing two chlorine substituents at the ortho and para positions of the aromatic ring. This configuration imparts enhanced electron-withdrawing character and improved metabolic stability, making it valuable for medicinal chemistry applications. The primary alcohol functionality enables straightforward derivatization through esterification or ether formation, facilitating its integration into complex molecular architectures.
2,4-Dichlorophenethyl alcohol serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles and functionalized aromatic scaffolds. Its benzylic hydroxyl group facilitates straightforward derivatization via esterification, etherification, or oxidation to the corresponding aldehyde. The ortho- and para-chlorine substituents provide sites for palladium-catalyzed cross-coupling reactions, enhancing its utility in late-stage functionalization. Bench-stable and compatible with standard purification protocols, it functions effectively in multi-step syntheses requiring moderate functional group tolerance.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: