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Structure of 815583-95-0
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2,8-Dichloro-4-methylquinoline features a rigid quinoline scaffold with electron-withdrawing chlorine atoms at positions 2 and 8, enhancing electrophilicity. The methyl group at C4 introduces steric and electronic modulation, enabling its use in transition metal-catalyzed coupling reactions and as a building block for functionalized heterocycles in medicinal chemistry.
2,8-Dichloro-4-methylquinoline serves as a versatile building block in medicinal chemistry and materials science, enabling efficient access to functionalized quinoline scaffolds. Its dichloro substitution pattern facilitates subsequent cross-coupling reactions, while the methyl group provides a handle for selective functionalization. The compound exhibits good bench stability and compatibility with standard reaction conditions, making it well-suited for iterative synthesis workflows and heterocycle elaboration in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: