Fmoc-Lys-OAll.HCl

Name: Fmoc-Lys-OAll.HCl
Brand: ChemScene
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CAS No. 815619-80-8
Cat. No. CS-W007020
Molecule weight444.95
Purity≥97%
MDL No.MFCD26793581

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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General Information

CAS No. 815619-80-8
Cat. No. CS-W007020
Purity ≥97%
MDL No. MFCD26793581
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₄H₂₉ClN₂O₄
Molecular Weight 444.95
Synonym(s) None
SMILES O=C([C@H](CCCCN)NC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O)OCC=C.Cl

Description

Fmoc-Lys-OAll.HCl features a fully protected lysine side chain with an allyl (OAll) group, enabling orthogonal deprotection during peptide synthesis. The Fmoc moiety ensures efficient stepwise chain elongation, while the allyl protection offers compatibility with mild cleavage conditions. This combination streamlines late-stage functionalization and simplifies purification in complex sequence assembly.

Application

Fmoc-Lys-OAll.HCl serves as a key building block in solid-phase peptide synthesis, offering a protected lysine side chain with orthogonal OAll (allyl) functionality. The Fmoc group enables efficient Nα-deprotection under mild basic conditions, while the OAll moiety allows selective removal via palladium-catalyzed deallylation. This dual protection strategy supports complex peptide assembly, including branched or cyclic architectures, and facilitates post-synthetic modifications. The HCl salt enhances stability and solubility for routine handling in synthetic workflows.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 90.65
LogP 4.1737
H_Acceptors 5
H_Donors 2
Rotatable_Bonds 10

Other Classifications

Bioactive Molecules Peptides

Building Blocks Functional Group Fmoc

Life Science Amino Acids and their Derivatives Lysine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

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Fmoc-Lys-OAll.HCl

CAS No. 815619-80-8

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