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Structure of 823221-93-8
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5-Bromo-2-chloro-4-(trifluoromethyl)pyridine is a halogenated pyridine derivative featuring orthogonal reactivity at multiple positions. The trifluoromethyl group imparts strong electron-withdrawing character, while the bromo and chloro substituents enable selective cross-coupling reactions under palladium catalysis. This compound serves as a key building block in the synthesis of advanced pharmaceutical intermediates and functionalized heterocycles.
5-Bromo-2-chloro-4-(trifluoromethyl)pyridine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its complementary halogen reactivity. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the ortho-halogen substitution pattern facilitates selective functionalization. Its bench-stable nature and compatibility with standard reaction conditions make it ideal for constructing complex heterocyclic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H332-H335-H317
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Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P304+P341-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: