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CS-W001157 4
Total: USD 88.00

Spiro[4.5]decane-7,9-dione

  • CAS No. 82683-51-0

  • Cat. No. CS-0155311
  • Molecule weight166.22
  • Purity≥97%
  • MDL No.MFCD03844397

*For research and further manufacturing use only, not for direct human use.

Spiro[4.5]decane-7,9-dione|CS-0155311

Structure of 82683-51-0

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General Information

  • CAS No. 82683-51-0
  • Cat. No. CS-0155311
  • Purity ≥97%
  • MDL No. MFCD03844397
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₄O₂
  • Molecular Weight 166.22
  • Synonym(s) None
  • SMILES C1CCC2(C1)CC(=O)CC(=O)C2

Description

Spiro[4.5]decane-7,9-dione features a rigid spirocyclic core with two carbonyl groups at the 7 and 9 positions, enabling precise spatial control in molecular design. This scaffold exhibits enhanced stability and defined three-dimensional geometry, making it valuable for medicinal chemistry and molecular architecture applications.

Application

Spiro[4.5]decane-7,9-dione serves as a rigid, bicyclic scaffold for medicinal chemistry and natural product synthesis. Its 1,3-dicarbonyl motif enables enolization and metal coordination, facilitating aldol reactions, Michael additions, and transition-metal-catalyzed functionalizations. The spirocyclic core provides conformational constraint and enhanced metabolic stability, making it valuable for building complex heterocycles and bioactive molecule libraries.

Synthesis

  • Route1
    • 1-Cyclopentylidenepropan-2-one|CS-0578529
      933-02-8
    • null|null
      105-53-3
    • ~80%
    • In-stock
      Spiro[4.5]decane-7,9-dione|CS-0155311
      82683-51-0

    References

    • Schank, Kurt; La Vecchia, Luigi; Lick, Carlo Helvetica Chimica Acta, 2001 , vol. 84, # 7 p. 2071 - 2088
  • Route2
    • null|null
      67570-15-4
    • ~%
    • In-stock
      Spiro[4.5]decane-7,9-dione|CS-0155311
      82683-51-0

    References

    • Schank, Kurt; La Vecchia, Luigi; Lick, Carlo Helvetica Chimica Acta, 2001 , vol. 84, # 7 p. 2071 - 2088
  • Route3
    • 1-(1-Hydroxycyclopentyl)propan-2-one|CS-0964364
      38134-31-5
    • ~%
    • In-stock
      Spiro[4.5]decane-7,9-dione|CS-0155311
      82683-51-0

    References

    • Schank, Kurt; La Vecchia, Luigi; Lick, Carlo Helvetica Chimica Acta, 2001 , vol. 84, # 7 p. 2071 - 2088

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   34.14
  • LogP   1.8689
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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