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CS-W001157 4
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5-Chloroindole-3-carboxaldehyde

  • CAS No. 827-01-0

  • Cat. No. CS-W004140
  • Purity≥96%
  • MDL No.MFCD00175291
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

5-Chloroindole-3-carboxaldehyde|CS-W004140

Structure of 827-01-0

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Description

5-Chloroindole-3-carboxaldehyde features a chlorinated indole core with a reactive aldehyde group at the 3-position, enabling direct coupling in heterocyclic synthesis. This bench-stable derivative integrates readily into bioactive molecule scaffolds, offering enhanced electronic effects and improved solubility for downstream functionalization.

Application

5-Chloroindole-3-carboxaldehyde serves as a versatile building block for the synthesis of biologically active heterocycles and pharmaceutical intermediates. The aldehyde functionality enables efficient coupling reactions, while the chlorinated indole core provides enhanced electronic properties and metabolic stability. Its bench-stable nature and compatibility with standard functional group transformations make it well-suited for medicinal chemistry campaigns and scale-up applications.

General Information

  • CAS No. 827-01-0
  • Cat. No. CS-W004140
  • Purity ≥96%
  • MDL No. MFCD00175291
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆ClNO
  • Molecular Weight 179.60
  • Synonym(s) 5-Chloro-3-formylindole
  • SMILES O=Cc1c[nH]c2c1cc(Cl)cc2

Computational Chemistry Data

  • TPSA   32.86
  • LogP   2.6338
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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