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Structure of 830-43-3
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4-(Trifluoromethyl)benzenesulfonamide features a strongly electron-deficient aryl ring flanked by a sulfonamide group, enabling robust hydrogen bonding and enhanced solubility in polar solvents. This combination delivers high stability under standard bench conditions, facilitating its use in medicinal chemistry and as a building block for bioactive compounds.
4-(Trifluoromethyl)benzenesulfonamide serves as a robust sulfonamide building block in medicinal chemistry, enabling efficient construction of biologically active scaffolds. Its trifluoromethyl group enhances metabolic stability and modulates lipophilicity, while the sulfonamide moiety provides strong hydrogen-bonding capacity and favorable pharmacokinetic properties. The compound exhibits excellent bench stability and compatibility with standard coupling reactions, facilitating straightforward purification and integration into diverse synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: