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Structure of 832114-04-2
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This boronate ester features a trifluoromethoxy-substituted aryl group and a tetramethyl-dioxaborolane core, enabling stable coupling in Suzuki-Miyaura reactions. The electron-deficient phenyl ring enhances reactivity, while the steric bulk of the methyl groups improves shelf life and handling under standard conditions.
4,4,5,5-Tetramethyl-2-(2-(trifluoromethoxy)phenyl)-1,3,2-dioxaborolane serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. Its trifluoromethoxy-substituted aryl group enables efficient C–C bond formation with diverse aryl halides and pseudohalides under standard catalytic conditions. The tetramethyl substituents enhance stability and solubility, while the dioxaborolane ring facilitates mild activation and high functional group tolerance, making it ideal for constructing complex heterocyclic and pharmaceutical scaffolds in iterative synthesis workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: