N-Boc-D-prolinol

Name: N-Boc-D-prolinol
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 83435-58-9
Cat. No. CS-D1199
Purity≥97%
MDL No.MFCD00040580

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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General Information

CAS No. 83435-58-9
Cat. No. CS-D1199
Purity ≥97%
MDL No. MFCD00040580
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₉NO₃
Molecular Weight 201.27
Synonym(s) None
SMILES O=C(N1[C@H](CCC1)CO)OC(C)(C)C

Description

N-Boc-D-prolinol features a protected D-proline scaffold with a hydroxyl group, offering enhanced stability and solubility in polar solvents. This bench-stable derivative simplifies incorporation into asymmetric synthesis workflows, enabling efficient access to chiral building blocks for pharmaceutical intermediates and catalyst design.

Application

N-Boc-D-prolinol serves as a versatile chiral building block in asymmetric synthesis, enabling efficient access to D-proline-derived heterocycles and peptidomimetics. Its Boc-protected amine offers excellent bench stability and compatibility with standard coupling conditions, while the hydroxyl group facilitates selective derivatization and orthogonal functionalization. This scaffold is widely employed in catalytic systems and medicinal chemistry campaigns requiring stereocontrolled synthesis of bioactive molecules.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 49.77
LogP 1.3782
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Bioactive Molecules Dye and Bio-assay Reagents

Life Science Amino Acids and their Derivatives Proline and derivatives

Building Blocks Functional Group Boc

Building Blocks Functional Group Alcohol

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

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N-Boc-D-prolinol

CAS No. 83435-58-9

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