N-Boc-D-prolinol

Name: N-Boc-D-prolinol
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 83435-58-9
Cat. No. CS-D1199
Purity≥97%
MDL No.MFCD00040580

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HazMat Fee

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 83435-58-9

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Description

N-Boc-D-prolinol features a protected D-proline scaffold with a hydroxyl group, offering enhanced stability and solubility in polar solvents. This bench-stable derivative simplifies incorporation into asymmetric synthesis workflows, enabling efficient access to chiral building blocks for pharmaceutical intermediates and catalyst design.

Application

N-Boc-D-prolinol serves as a versatile chiral building block in asymmetric synthesis, enabling efficient access to D-proline-derived heterocycles and peptidomimetics. Its Boc-protected amine offers excellent bench stability and compatibility with standard coupling conditions, while the hydroxyl group facilitates selective derivatization and orthogonal functionalization. This scaffold is widely employed in catalytic systems and medicinal chemistry campaigns requiring stereocontrolled synthesis of bioactive molecules.

General Information

CAS No. 83435-58-9
Cat. No. CS-D1199
Purity ≥97%
MDL No. MFCD00040580
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₉NO₃
Molecular Weight 201.27
Synonym(s) None
SMILES O=C(N1[C@H](CCC1)CO)OC(C)(C)C

Computational Chemistry Data

TPSA 49.77
LogP 1.3782
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Dye and Bio-assay Reagents

Building Blocks Functional Group Boc

Building Blocks Functional Group Alcohol

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Proline and derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

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N-Boc-D-prolinol

CAS No. 83435-58-9

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