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CS-W001157 4
Total: USD 88.00

Valiolamine

  • CAS No. 83465-22-9

  • Cat. No. CS-0128609
  • Molecule weight193.20
  • Purity≥97%
  • MDL No.MFCD07773061

*For research and further manufacturing use only, not for direct human use.

Valiolamine|CS-0128609

Structure of 83465-22-9

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General Information

  • CAS No. 83465-22-9
  • Cat. No. CS-0128609
  • Purity ≥97%
  • MDL No. MFCD07773061
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₅NO₅
  • Molecular Weight 193.20
  • Synonym(s) None
  • SMILES O[C@H]1[C@@](C[C@@H](N)[C@H]([C@@H]1O)O)(CO)O

Description

Valiolamine features a rigid, bicyclic scaffold with a strategically positioned hydroxylated amine moiety, enabling robust hydrogen bonding and enhanced solubility in aqueous-organic mixtures. This configuration supports efficient conjugation chemistry and stability under physiological conditions, making it well-suited for use in glycoconjugate synthesis and targeted delivery systems.

Application

Valiolamine serves as a versatile scaffold for the synthesis of bioactive heterocycles and glycomimetics, leveraging its rigid, polyhydroxylated structure to facilitate stereoselective transformations. Its stability under standard reaction conditions and compatibility with common protecting group strategies enable efficient access to complex molecular architectures relevant in medicinal chemistry and natural product synthesis.

Synthesis

  • Route1
    • null|null
      140926-94-9
    • ~%
    • In-stock
      Valiolamine|CS-0128609
      83465-22-9

    References

    • WO2005/49547 A1, ; Page/Page column 18 ;
  • Route2
    • null|null
      1060713-64-5
    • ~90%
    • In-stock
      Valiolamine|CS-0128609
      83465-22-9

    References

    • Shing, Tony K. M.; Cheng, Hau M. Organic Letters, 2008 , vol. 10, # 18 p. 4137 - 4139
  • Route3
    • null|null
      183505-14-8
    • ~78%
    • In-stock
      Valiolamine|CS-0128609
      83465-22-9

    References

    • Shing, Tony K. M.; Wan, Leong H. Journal of Organic Chemistry, 1996 , vol. 61, # 24 p. 8468 - 8479

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   127.17
  • LogP   -3.4765
  • H_Acceptors   6
  • H_Donors   6
  • Rotatable_Bonds   1

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