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Structure of 83487-42-7
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2-Iodo-N-methylacetamide is a reactive iodide-containing amide featuring a methylated nitrogen and a labile iodo substituent. This compound integrates readily into cross-coupling reactions, enabling efficient access to functionalized acetamides under mild conditions. Its bench-stable nature facilitates handling in synthetic workflows requiring precise halogenation control.
2-Iodo-N-methylacetamide serves as a versatile iodinated building block for late-stage functionalization and cross-coupling reactions. Its iodide group enables reliable Suzuki, Stille, and Negishi coupling protocols under standard conditions, while the N-methyl amide functionality provides enhanced metabolic stability and solubility in medicinal chemistry applications. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis workflows in API development and heterocycle construction.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P405-P501
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Lot numbers can be found on the outside label of a product: