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Structure of 69361-41-7
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4-Bromo-1-trimethylsilyl-1-butyne features a terminal alkyne anchored by a trimethylsilyl group, enabling stable storage and selective activation. The bromine substituent provides a reactive handle for cross-coupling transformations. This molecule integrates seamlessly into Sonogashira and other palladium-catalyzed reactions, delivering efficient access to functionalized alkynes under mild conditions.
4-Bromo-1-trimethylsilyl-1-butyne serves as a versatile building block in palladium-catalyzed cross-coupling reactions, enabling efficient synthesis of conjugated enynes and functionalized alkynes. The trimethylsilyl group provides enhanced stability and facilitates mild deprotection, while the terminal alkyne and bromine handle offer orthogonal reactivity for sequential transformations. Its bench-stable nature and compatibility with standard coupling protocols make it ideal for complex molecule assembly in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS02
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H225-H315-H319-H335
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Precautionary Statements : P210-P240-P241-P242-P243-P261-P271-P280-P302+P352-P304+P340-P362-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: