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Structure of 834917-24-7
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N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(1R,2R)-2-(dimethylamino)-1,2-diphenylethyl]thiourea features a sterically hindered thiourea core flanked by electron-deficient aryl and bulky chiral diphenylalkyl moieties. This configuration enables precise molecular recognition in supramolecular systems, delivering enhanced binding affinity and selectivity under standard conditions.
N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(1R,2R)-2-(dimethylamino)-1,2-diphenylethyl]thiourea serves as a versatile scaffold in medicinal chemistry, enabling efficient access to bioactive heterocycles through standard coupling and cyclization protocols. Its trifluoromethylated aryl moiety enhances metabolic stability and lipophilicity, while the chiral diphenylethyl amine framework supports stereocontrolled synthesis. The thiourea functionality offers strong hydrogen-bonding capacity and facilitates purification via crystallization or chromatography, making it well-suited for high-throughput screening campaigns and lead optimization workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: