Thalidomide 4-fluoride

Name: Thalidomide 4-fluoride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 835616-60-9
Cat. No. CS-B1597
Purity≥95%
MDL No.MFCD11840666

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 835616-60-9

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 835616-60-9
Cat. No. CS-B1597
Purity ≥95%
MDL No. MFCD11840666
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₉FN₂O₄
Molecular Weight 276.22
Synonym(s) Cereblon ligand 4; E3 ligase Ligand 4
SMILES O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3F)=O

Description

Thalidomide 4-fluoride features a fluorinated analog of thalidomide, where the para-fluoro substitution enhances metabolic stability and modulates target engagement. This derivative retains the core immunomodulatory scaffold while improving pharmacokinetic properties for research applications in oncology and inflammatory disease modeling.

Application

Thalidomide 4-fluoride serves as a fluorinated analog of thalidomide, enabling targeted exploration of structure-activity relationships within the glutarimide class. Its enhanced metabolic stability and modulated electronic properties facilitate studies in protein degradation pathways, particularly in the context of cereblon-mediated E3 ligase recruitment. The compound functions as a valuable tool for probing the influence of fluorine substitution on pharmacokinetics and target engagement in oncology and immunomodulatory research.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 83.55
LogP 0.2102
H_Acceptors 6
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Bioactive Molecules Bioactive Small Molecules

Life Science PROTAC Ligands for E3 Ligase

Life Science Linker PROTAC Linkers

Building Blocks Functional Group Fluoride

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Indole compounds

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Proteolysis Targeting Chimera Research Reagents

Biochemistry Pharmaceutical Development and Drug Discovery Research Proteolysis Targeting Chimera Research Reagents

Key Words

Thalidomide 4-fluoride sigmaThalidomide 4-fluoride manufacturerThalidomide 4-fluoride priceThalidomide 4-fluoride structureThalidomide 4-fluoride SDSbuy Thalidomide 4-fluorideThalidomide 4-fluoride supplierThalidomide 4-fluoride usesThalidomide 4-fluoride molecular weightprice of Thalidomide 4-fluorideThalidomide 4-fluoride chemical name formula of Thalidomide 4-fluoride

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Thalidomide 4-fluoride

CAS No. 835616-60-9

Recommended Products