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Structure of 842136-27-0
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5-Bromo-2,4-dimethylbenzoic acid features a bromine substituent at the 5-position paired with methyl groups at the 2- and 4-positions, creating a sterically hindered, electron-deficient aromatic core. This configuration enhances stability and facilitates selective coupling reactions in synthetic pathways. The carboxylic acid group enables direct derivatization or salt formation for improved solubility and handling.
5-Bromo-2,4-dimethylbenzoic acid serves as a versatile building block for pharmaceutical and agrochemical synthesis, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling reactions. Its ortho-methyl groups enhance steric control in coupling processes, while the carboxylic acid functionality facilitates direct derivatization or salt formation. The molecule exhibits excellent bench stability and compatibility with standard purification techniques, making it well-suited for iterative synthetic workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: