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Structure of 84315-24-2
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3-(3,5-Difluorophenyl)propionic acid features a trifluorinated aromatic core linked to a propionic acid chain, delivering enhanced metabolic stability and lipophilic character. This structural motif integrates readily into bioactive scaffolds, particularly in CNS-targeted therapeutics and kinase inhibitors. The electron-deficient phenyl ring improves binding affinity through favorable π-stacking interactions, while the carboxylic acid group enables direct conjugation or salt formation for improved solubility and handling.
3-(3,5-Difluorophenyl)propionic acid serves as a valuable building block in medicinal chemistry, enabling the synthesis of bioactive molecules through standard functional group transformations. Its fluorinated aryl moiety enhances metabolic stability and modulates lipophilicity, while the carboxylic acid functionality facilitates coupling reactions, esterification, and amide formation. The compound exhibits good bench stability and is compatible with common purification techniques, making it a practical choice for iterative synthetic workflows.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302+H312-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: