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CS-W001157 4
Total: USD 88.00

Raloxifene impurity 7

  • CAS No. 84449-80-9

  • Cat. No. CS-W021983
  • Molecule weight285.77
  • Purity≥98%
  • MDL No.MFCD06657755

*For research and further manufacturing use only, not for direct human use.

Raloxifene impurity 7|CS-W021983

Structure of 84449-80-9

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General Information

  • CAS No. 84449-80-9
  • Cat. No. CS-W021983
  • Purity ≥98%
  • MDL No. MFCD06657755
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₀ClNO₃
  • Molecular Weight 285.77
  • Synonym(s) None
  • SMILES Cl.O=C(O)C1=CC=C(OCCN2CCCCC2)C=C1

Application

4-(2-(Piperidin-1-yl)ethoxy)benzoic acid hydrochloride serves as a versatile building block for medicinal chemistry, enabling efficient access to bioactive scaffolds through standard amide coupling and derivatization protocols. The piperidinylethoxy side chain provides enhanced solubility and metabolic stability, while the carboxylic acid functionality facilitates direct conjugation or salt formation. Bench-stable and compatible with common purification methods, it functions reliably in peptide-like and heterocyclic synthesis workflows.

Synthesis

  • Route1
    • null|null
      93148-78-8
    • 2-Piperidinoethyl chloride hydrochloride Raloxifene  Impurity|CS-0229092
      2008-75-5
    • In-stock
      Methyl paraben, ≥99%|CS-1268984
      99-76-3
    • ~89%
    • In-stock
      Raloxifene impurity 7|CS-W021983
      84449-80-9

    References

    • Eli Lilly and Company Patent: US5631369 A1, 1997 ;
  • Route2
    • 2-Piperidinoethyl chloride hydrochloride Raloxifene  Impurity|CS-0229092
      2008-75-5
    • In-stock
      Methyl paraben, ≥99%|CS-1268984
      99-76-3
    • ~96%
    • Methyl 4-(2-(piperidin-1-yl)ethoxy)benzoate|CS-1701066
      89407-97-6
    • In-stock
      Raloxifene impurity 7|CS-W021983
      84449-80-9

    References

    • Eli Lilly and Company Patent: US5631369 A1, 1997 ;
  • Route3
    • null|null
      93148-78-8
    • ~82%
    • In-stock
      Raloxifene impurity 7|CS-W021983
      84449-80-9

    References

    • Eli Lilly and Company Patent: US6372945 B1, 2002 ; Location in patent: Page column 16 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.77
  • LogP   2.6713
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   5

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