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Structure of 84487-08-1
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4-Methoxy-3-nitropyridin-2-amine features a pyridine core bearing a methoxy group at C4 and a nitro substituent at C3, positioned ortho to the aniline nitrogen. This electron-deficient heterocycle integrates readily into cross-coupling workflows and serves as a key intermediate in the synthesis of bioactive nitrogen-containing scaffolds.
4-Methoxy-3-nitropyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to functionalized pyridine scaffolds. Its ortho-directing amino group and electron-withdrawing nitro functionality facilitate selective metal-catalyzed couplings and sequential transformations. The methoxy substituent enhances solubility and modulates electronic properties, while the molecule exhibits sufficient bench stability for routine handling and purification.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: