6-Chloro-N-methylpicolinamide

Name: 6-Chloro-N-methylpicolinamide
Brand: ChemScene
Availability: InStock
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CAS No. 845306-04-9
Cat. No. CS-0151056
Purity≥98%
MDL No.MFCD09862945

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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6-Chloro-N-methylpicolinamide|CS-0151056

Structure of 845306-04-9

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Description

6-Chloro-N-methylpicolinamide features a chlorinated pyridine ring paired with a methylated amide group, delivering enhanced electron-withdrawing character and improved solubility. This combination enables efficient integration into pharmaceutical intermediates and synthetic scaffolds under standard conditions.

Application

6-Chloro-N-methylpicolinamide serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds through direct functionalization at the C6 position. Its chloro group facilitates palladium-catalyzed cross-coupling reactions, while the N-methylamide moiety provides enhanced metabolic stability and favorable solubility profiles. The compound exhibits excellent bench stability and compatibility with standard synthetic protocols, facilitating straightforward purification and integration into complex molecule synthesis.

General Information

CAS No. 845306-04-9
Cat. No. CS-0151056
Purity ≥98%
MDL No. MFCD09862945
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₇ClN₂O
Molecular Weight 170.60
Synonym(s) 6-chloro-N-methylpyridine-2-carboxamide
SMILES CNC(=O)C1=NC(=CC=C1)Cl

Computational Chemistry Data

TPSA 41.99
LogP 1.0946
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Amide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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6-Chloro-N-methylpicolinamide

CAS No. 845306-04-9

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