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Structure of 84743-77-1
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2-Bromobenzene-1,3,5-triol features a bromine substituent flanked by three hydroxyl groups on a benzene ring, creating a highly polar, electron-deficient scaffold. This arrangement enables direct coupling in cross-coupling reactions and serves as a key intermediate for functionalized aromatic systems in medicinal chemistry and materials science.
2-Bromobenzene-1,3,5-triol serves as a versatile trifunctional building block for the synthesis of complex heterocycles and bioactive scaffolds. Its ortho-bromo and three phenolic hydroxyl groups enable selective metal-catalyzed coupling reactions, directed ortho-metalation, and regioselective derivatization. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302+H312+H332-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: