2,4-Difluoro-3-methylbenzonitrile

Name: 2,4-Difluoro-3-methylbenzonitrile
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 847502-87-8
Cat. No. CS-W003421
Purity≥98%
MDL No.MFCD07777155

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2,4-Difluoro-3-methylbenzonitrile|CS-W003421

Structure of 847502-87-8

Size

Price

Quantity

* Please select Quantity before adding items.

Description

2,4-Difluoro-3-methylbenzonitrile features a trifunctional aromatic core with strategically positioned fluorine atoms and a methyl group that modulate electronic properties. The nitrile moiety provides a robust handle for downstream functionalization, while the electron-deficient ring enhances reactivity in cross-coupling processes. This bench-stable compound serves as a key building block in agrochemical and pharmaceutical synthesis.

Application

2,4-Difluoro-3-methylbenzonitrile serves as a versatile building block in medicinal chemistry, enabling the construction of fluorinated aromatic scaffolds via standard cross-coupling and electrophilic substitution reactions. Its regioselective substitution pattern and compatibility with palladium-catalyzed transformations facilitate efficient synthesis of complex heterocycles and API intermediates. The nitrile group provides a handle for downstream functionalization, while the methyl and difluoro substituents offer favorable electronic and steric profiles for target-directed design.

General Information

CAS No. 847502-87-8
Cat. No. CS-W003421
Purity ≥98%
MDL No. MFCD07777155
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₅F₂N
Molecular Weight 153.13
Synonym(s) 3-Cyano-2,6-difluorotoluene
SMILES CC1=C(F)C=CC(C#N)=C1F

Computational Chemistry Data

TPSA 23.79
LogP 2.1449
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS06
Signal Word : Danger	UN#: 3439
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H302-H312-H315-H319-H331-H335
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Cyanide/Nitrile

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

2,4-Difluoro-3-methylbenzonitrile sigma2,4-Difluoro-3-methylbenzonitrile manufacturer2,4-Difluoro-3-methylbenzonitrile price2,4-Difluoro-3-methylbenzonitrile structure2,4-Difluoro-3-methylbenzonitrile SDSbuy 2,4-Difluoro-3-methylbenzonitrile2,4-Difluoro-3-methylbenzonitrile supplier2,4-Difluoro-3-methylbenzonitrile uses2,4-Difluoro-3-methylbenzonitrile molecular weightprice of 2,4-Difluoro-3-methylbenzonitrile2,4-Difluoro-3-methylbenzonitrile chemical name formula of 2,4-Difluoro-3-methylbenzonitrile

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2,4-Difluoro-3-methylbenzonitrile

CAS No. 847502-87-8

Recommended Products