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Structure of 84758-55-4
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Methyl 2-((tert-butoxycarbonyl)amino)-2-methylpropanoate is a bench-stable, moisture-tolerant amino acid equivalent featuring a sterically hindered α-carbon. This protected serine surrogate integrates seamlessly into peptide synthesis workflows, enabling efficient coupling and selective deprotection under mild acidic conditions. The tert-butyl carbamate group provides robust protection for the amine, while the methyl ester facilitates downstream functionalization.
Methyl 2-((tert-butoxycarbonyl)amino)-2-methylpropanoate serves as a stable, bench-ready building block for the synthesis of sterically hindered amino acid derivatives and peptidomimetics. The tert-butyl carbamate (Boc) group enables orthogonal protection of primary amines, while the methyl ester supports facile hydrolysis or coupling reactions. Its resistance to racemization and compatibility with standard peptide coupling protocols makes it ideal for modular solid-phase and solution-phase syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: