1H-Pyrrolo[2,3-b]pyridin-5-ylmethanol

Name: 1H-Pyrrolo[2,3-b]pyridin-5-ylmethanol
Brand: ChemScene
Availability: InStock
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CAS No. 849067-97-6
Cat. No. CS-0002365
Purity≥98%
MDL No.MFCD08457786

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Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
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1H-Pyrrolo[2,3-b]pyridin-5-ylmethanol|CS-0002365

Structure of 849067-97-6

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Description

1H-Pyrrolo[2,3-b]pyridin-5-ylmethanol offers a rigid heteroaromatic scaffold with a pendant hydroxymethyl group, enabling direct functionalization or conjugation in synthetic routes. This bench-stable building block integrates readily into bioactive molecule frameworks, particularly in medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.

Application

1H-Pyrrolo[2,3-b]pyridin-5-ylmethanol serves as a versatile building block for heterocyclic synthesis, enabling efficient functionalization at the benzylic position. Its stability under standard reaction conditions and compatibility with diverse coupling and oxidation protocols facilitate access to complex scaffolds relevant in medicinal chemistry. The molecule functions effectively as a key intermediate in the construction of bioactive pyrrolopyridine derivatives.

General Information

CAS No. 849067-97-6
Cat. No. CS-0002365
Purity ≥98%
MDL No. MFCD08457786
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₈N₂O
Molecular Weight 148.16
Synonym(s) (1H-Pyrrolo[2,3-B]Pyridin-5-YL)-Methanol
SMILES OCC1=CN=C(NC=C2)C2=C1

Computational Chemistry Data

TPSA 48.91
LogP 1.0552
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 1

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrrole compounds

Key Words

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1H-Pyrrolo[2,3-b]pyridin-5-ylmethanol

CAS No. 849067-97-6

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