tert-Butyl 5-bromo-3-iodo-1H-indole-1-carboxylate

Name: tert-Butyl 5-bromo-3-iodo-1H-indole-1-carboxylate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 850349-72-3
Cat. No. CS-0045064
Purity≥95%
MDL No.MFCD05864761

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 5-bromo-3-iodo-1H-indole-1-carboxylate|CS-0045064

Structure of 850349-72-3

Size

Price

Quantity

* Please select Quantity before adding items.

Description

tert-Butyl 5-bromo-3-iodo-1H-indole-1-carboxylate features a sterically hindered tert-butyl ester and dual halogen substituents at the 5- and 3-positions of the indole core, enabling selective cross-coupling reactions. The electron-deficient indole scaffold supports efficient Pd-catalyzed transformations, while the bench-stable functionality simplifies handling in synthetic workflows.

Application

tert-Butyl 5-bromo-3-iodo-1H-indole-1-carboxylate serves as a versatile building block for the synthesis of substituted indoles, enabling sequential cross-coupling reactions via orthogonal halogen reactivity. The bromo and iodo groups facilitate palladium-catalyzed coupling processes with high chemoselectivity, while the tert-butyl carbamate protects the nitrogen under standard reaction conditions. This compound exhibits excellent bench stability and is readily purified by flash chromatography, making it well-suited for iterative medicinal chemistry campaigns and API intermediate development.

General Information

CAS No. 850349-72-3
Cat. No. CS-0045064
Purity ≥95%
MDL No. MFCD05864761
Storage -20°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₁₃BrINO₂
Molecular Weight 422.06
Synonym(s) tert-butyl 5-bromo-3-iodo-indole-1-carboxylate
SMILES O=C(N1C=C(I)C2=C1C=CC(Br)=C2)OC(C)(C)C

Computational Chemistry Data

TPSA 31.23
LogP 4.7916
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Iodide

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Indole compounds

Key Words

850349-72-3 sigma850349-72-3 manufacturer850349-72-3 price850349-72-3 structure850349-72-3 SDSbuy 850349-72-3850349-72-3 supplier850349-72-3 uses850349-72-3 molecular weightprice of 850349-72-3850349-72-3 chemical name formula of 850349-72-3

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

tert-Butyl 5-bromo-3-iodo-1H-indole-1-carboxylate

CAS No. 850349-72-3

Recommended Products