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CS-W001157 4
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5-(Cyclopropylmethoxy)-1H-pyrazol-3-amine

  • CAS No. 852443-66-4

  • Cat. No. CS-0119828
  • Molecule weight153.18
  • Purity≥98%
  • MDL No.MFCD20724093

*For research and further manufacturing use only, not for direct human use.

5-(Cyclopropylmethoxy)-1H-pyrazol-3-amine|CS-0119828

Structure of 852443-66-4

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General Information

  • CAS No. 852443-66-4
  • Cat. No. CS-0119828
  • Purity ≥98%
  • MDL No. MFCD20724093
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₁N₃O
  • Molecular Weight 153.18
  • Synonym(s) 5-cyclopropylmethoxy-1H-pyrazol-3-yl-amine
  • SMILES NC1=NNC(OCC2CC2)=C1

Description

5-(Cyclopropylmethoxy)-1H-pyrazol-3-amine features a pyrazole core with a strategically positioned amino group and a cyclopropylmethyl ether substituent. This combination imparts enhanced solubility and metabolic stability, making it a valuable scaffold in medicinal chemistry. The molecule integrates readily into diverse heterocyclic systems under standard coupling conditions.

Application

5-(Cyclopropylmethoxy)-1H-pyrazol-3-amine serves as a versatile building block for medicinal chemistry, enabling the construction of pyrazole-based scaffolds with enhanced solubility and metabolic stability. Its ortho-amino functionality facilitates downstream coupling reactions, while the cyclopropylmethyl ether group offers favorable steric and lipophilic properties for target optimization. The compound exhibits good bench stability and is compatible with standard purification methods.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   63.93
  • LogP   0.7807
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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