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Structure of 854690-87-2
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This boronate moiety integrates a difluoromethyl group at the meta position of a phenyl ring, delivering enhanced stability and moisture tolerance. The electron-deficient arylboronic acid enables efficient Suzuki-Miyaura cross-coupling under standard conditions, offering reliable access to functionalized biaryls in medicinal chemistry and materials synthesis.
(3-(Difluoromethyl)phenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds with enhanced metabolic stability. The difluoromethyl group imparts favorable electronic and lipophilic properties, while the boronic acid functionality offers excellent bench stability and compatibility with diverse reaction conditions. Its predictable reactivity facilitates straightforward purification and integration into complex molecule synthesis.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H315-H318-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: