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Structure of 946525-43-5
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This boronate moiety integrates a difluoromethyl group at the para position of a phenyl ring, delivering enhanced metabolic stability and electron-deficient character. The functional group enables efficient Suzuki-Miyaura coupling under standard conditions, facilitating rapid access to fluorinated biaryl scaffolds in medicinal chemistry and materials science applications.
(4-(Difluoromethyl)phenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds with enhanced metabolic stability. The difluoromethyl group imparts favorable electronic and lipophilic properties, improving bioavailability in medicinal chemistry applications. Its bench-stable nature and compatibility with diverse functional groups facilitate straightforward purification and integration into complex molecular architectures.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H315-H318-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: