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Structure of 854778-31-7
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4-Fluoro-3-methoxybenzeneboronic acid features a strategically positioned boronic acid group flanked by electron-withdrawing fluorine and electron-donating methoxy substituents, enabling selective cross-coupling reactivity in Suzuki-Miyaura transformations. The ortho-fluoro substitution enhances stability under basic conditions while maintaining high functional group tolerance. This bench-stable reagent integrates efficiently into complex molecule synthesis workflows, particularly for pharmaceutical intermediates requiring precise stereochemical control and metabolic resistance.
4-Fluoro-3-methoxybenzeneboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its ortho-fluoro and meta-methoxy substituents provide predictable regiochemistry and enhanced stability during storage and handling. The boronic acid functionality exhibits excellent functional group tolerance and facilitates straightforward purification, making it well-suited for the synthesis of biaryl scaffolds in pharmaceutical and agrochemical research.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: