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Structure of 857267-04-0
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1-(Propan-2-yl)-1H-pyrazol-3-amine features a sterically hindered isopropyl group flanking a pyrazole nitrogen, enhancing stability and solubility in organic media. This bench-stable scaffold integrates readily into heterocyclic architectures, serving as a key building block for bioactive molecules in medicinal chemistry and agrochemical development.
1-(Propan-2-yl)-1H-pyrazol-3-amine serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyrazole-based scaffolds with demonstrated utility in kinase inhibitor and CNS-targeted drug discovery. The tertiary isopropyl group enhances metabolic stability and lipophilicity, while the primary amine facilitates straightforward derivatization via acylation, alkylation, or coupling reactions. This compound exhibits excellent bench stability, ease of purification, and compatibility with standard synthetic workflows, making it a reliable intermediate for targeted compound library generation.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: