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CS-W001157 4
Total: USD 88.00

2-Methyl-oxazole-4-carboxylic acid methyl ester

  • CAS No. 85806-67-3

  • Cat. No. CS-W003035
  • Purity≥98%
  • MDL No.MFCD03265460
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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

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*For research and further manufacturing use only, not for direct human use.

2-Methyl-oxazole-4-carboxylic acid methyl ester|CS-W003035

Structure of 85806-67-3

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Description

2-Methyl-oxazole-4-carboxylic acid methyl ester features a polar oxazole core with a methyl substituent at the 2-position and an ester group at C4, enabling direct integration into heterocyclic synthesis. The electron-deficient oxazole ring enhances reactivity in cross-coupling and nucleophilic substitution processes. This bench-stable, moisture-tolerant reagent streamlines access to bioactive scaffolds in medicinal chemistry.

Application

2-Methyl-oxazole-4-carboxylic acid methyl ester serves as a versatile building block in heterocyclic synthesis, enabling efficient access to oxazole-based scaffolds prevalent in medicinal chemistry. Its methyl ester functionality facilitates straightforward derivatization via hydrolysis or nucleophilic substitution, while the 2-methyl group enhances stability and modulates reactivity. The compound exhibits excellent bench stability, compatibility with standard coupling conditions, and ease of purification—making it well-suited for iterative synthesis workflows and API precursor development.

General Information

  • CAS No. 85806-67-3
  • Cat. No. CS-W003035
  • Purity ≥98%
  • MDL No. MFCD03265460
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇NO₃
  • Molecular Weight 141.12
  • Synonym(s) Methyl 2-methyloxazole-4-carboxylate
  • SMILES COC(=O)c1coc(n1)C

Computational Chemistry Data

  • TPSA   52.33
  • LogP   0.76962
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335-H412
Precautionary Statements : P261-P264-P271-P273-P280-P302+P352-P304+P340-P362+P364-P405-P501

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