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Structure of 460081-18-9
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Ethyl 2-chlorooxazole-4-carboxylate features a chlorinated oxazole core enabling direct functionalization at the 2-position. This bench-stable, moisture-tolerant heterocycle integrates readily into synthetic sequences requiring electrophilic substitution or transition-metal-catalyzed coupling. The ethyl ester group provides compatibility with standard reduction and amidation protocols.
Ethyl 2-chlorooxazole-4-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to oxazole-based scaffolds through nucleophilic substitution and transition-metal-catalyzed coupling reactions. Its chlorine at the C2 position exhibits high reactivity toward amines, thiols, and organometallic reagents, facilitating rapid diversification. The ester group allows for selective transformations under mild conditions, enhancing functional group tolerance and simplifying purification. This compound demonstrates excellent bench stability and compatibility with standard synthetic workflows, making it ideal for medicinal chemistry and process development applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: