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Structure of 85806-67-3
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2-Methyl-oxazole-4-carboxylic acid methyl ester features a polar oxazole core with a methyl substituent at the 2-position and an ester group at C4, enabling direct integration into heterocyclic synthesis. The electron-deficient oxazole ring enhances reactivity in cross-coupling and nucleophilic substitution processes. This bench-stable, moisture-tolerant reagent streamlines access to bioactive scaffolds in medicinal chemistry.
2-Methyl-oxazole-4-carboxylic acid methyl ester serves as a versatile building block in heterocyclic synthesis, enabling efficient access to oxazole-based scaffolds prevalent in medicinal chemistry. Its methyl ester functionality facilitates straightforward derivatization via hydrolysis or nucleophilic substitution, while the 2-methyl group enhances stability and modulates reactivity. The compound exhibits excellent bench stability, compatibility with standard coupling conditions, and ease of purification—making it well-suited for iterative synthesis workflows and API precursor development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335-H412
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Precautionary Statements : P261-P264-P271-P273-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: