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Methyl 4-((tert-butoxycarbonyl)amino)butanoate

  • CAS No. 85909-04-2

  • Cat. No. CS-0154367
  • Molecule weight217.27
  • Purity≥97%
  • MDL No.MFCD18206247

*For research and further manufacturing use only, not for direct human use.

Methyl 4-((tert-butoxycarbonyl)amino)butanoate|CS-0154367

Structure of 85909-04-2

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General Information

  • CAS No. 85909-04-2
  • Cat. No. CS-0154367
  • Purity ≥97%
  • MDL No. MFCD18206247
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₉NO₄
  • Molecular Weight 217.27
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCCCC(=O)OC

Description

Methyl 4-((tert-butoxycarbonyl)amino)butanoate is a protected amino acid derivative featuring a tert-butyl carbamate group flanking a primary amine. This stable, bench-ready reagent integrates readily into peptide synthesis workflows, enabling selective coupling and subsequent deprotection under mild acidic conditions. Its solubility in common organic solvents supports efficient reaction handling and purification.

Application

Methyl 4-((tert-butoxycarbonyl)amino)butanoate serves as a versatile building block in peptide and heterocyclic synthesis, enabling efficient construction of γ-amino acid derivatives. The tert-butyl carbamate (Boc) group provides excellent stability under basic conditions and facilitates selective deprotection, while the ester moiety supports diverse transformations including hydrolysis, reduction, and coupling reactions. Its bench-stable nature and compatibility with standard synthetic workflows make it ideal for multi-step sequences in medicinal chemistry and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   64.63
  • LogP   1.4643
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   4

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