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Structure of 85943-26-6
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5-(tert-Butyl)-2-methoxybenzaldehyde features a sterically hindered tert-butyl group and a methoxy substituent positioned ortho to the aldehyde, enhancing electron density at the carbonyl. This combination imparts excellent stability under standard bench conditions while enabling selective coupling reactions in complex synthesis. The molecule integrates readily into multi-step pathways requiring controlled reactivity and resistance to oxidation.
5-(tert-Butyl)-2-methoxybenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, offering enhanced lipophilicity and steric bulk via the tert-butyl group. The aldehyde functionality enables efficient transformations including reductive amination, Grignard additions, and Wittig reactions. Its methoxy substituent provides moderate electron donation, while the ortho-methoxy and para-tert-butyl arrangement ensures excellent bench stability and ease of purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302+H312+H332-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: