2-Chloro-4-fluorobenzene-1-sulfonyl chloride

Name: 2-Chloro-4-fluorobenzene-1-sulfonyl chloride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 85958-57-2
Cat. No. CS-0022408
Purity≥96%
MDL No.MFCD00052957

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Chloro-4-fluorobenzene-1-sulfonyl chloride|CS-0022408

Structure of 85958-57-2

Size

Price

Quantity

* Please select Quantity before adding items.

Description

2-Chloro-4-fluorobenzene-1-sulfonyl chloride features a dual halogenated aromatic core with reactive sulfonyl chloride functionality. This electrophilic reagent enables efficient sulfonamide formation under mild conditions, offering high chemoselectivity in complex molecule synthesis. The ortho-chloro and para-fluoro substituents enhance stability and modulate reactivity for precise functionalization.

Application

2-Chloro-4-fluorobenzene-1-sulfonyl chloride serves as a versatile sulfonylating agent for the introduction of sulfonamide groups in medicinal chemistry and agrochemical synthesis. Its ortho-chloro and para-fluoro substituents enhance reactivity while maintaining bench stability, enabling selective functionalization under mild conditions. The compound facilitates efficient coupling with amines to yield sulfonamides, which are key structural motifs in bioactive molecules. Its compatibility with diverse functional groups and straightforward purification make it a practical choice for high-yield transformations in multi-step syntheses.

General Information

CAS No. 85958-57-2
Cat. No. CS-0022408
Purity ≥96%
MDL No. MFCD00052957
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₃Cl₂FO₂S
Molecular Weight 229.06
Synonym(s) Disulfide, bis[2-nitro-4- (trifluoromethyl)phenyl]
SMILES O=S(C1=CC=C(F)C=C1Cl)(Cl)=O

Computational Chemistry Data

TPSA 34.14
LogP 2.4066
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05
Signal Word : Danger	UN#: 1759
Class : 8	Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Sulfonyl Chloride

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

85958-57-2 sigma85958-57-2 manufacturer85958-57-2 price85958-57-2 structure85958-57-2 SDSbuy 85958-57-285958-57-2 supplier85958-57-2 uses85958-57-2 molecular weightprice of 85958-57-285958-57-2 chemical name formula of 85958-57-2

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Chloro-4-fluorobenzene-1-sulfonyl chloride

CAS No. 85958-57-2

Recommended Products