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Structure of 860411-74-1
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2-(Hydroxymethyl)pyridin-4-ol features a pyridine ring bearing both hydroxyl and hydroxymethyl groups in a para arrangement, enabling dual functionalization. This scaffold delivers enhanced solubility and stability under standard conditions, facilitating integration into complex synthetic sequences. The phenolic hydroxyl group supports metal coordination and hydrogen bonding, while the adjacent hydroxymethyl moiety serves as a reactive handle for derivatization.
2-(Hydroxymethyl)pyridin-4-ol serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridine-based scaffolds through standard functional group interconversions. The ortho-hydroxy and hydroxymethyl groups provide complementary reactivity for derivatization, including oxidation to aldehyde, etherification, or coupling reactions. Its bench-stable nature and compatibility with common protecting group strategies facilitate reliable use in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319
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Precautionary Statements : P261-P302+P352
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Lot numbers can be found on the outside label of a product: