Lot numbers can be found on the outside label of a product:
(R)-2-((tert-Butoxycarbonyl)amino)-3-methoxypropanoic acid
-
CAS No. 86123-95-7
- Cat. No. CS-D0906
- Purity≥97%
- MDL No.MFCD08063987
*For research and further manufacturing use only, not for direct human use.
Structure of 86123-95-7
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 86123-95-7
- Cat. No. CS-D0906
- Purity ≥97%
- MDL No. MFCD08063987
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₉H₁₇NO₅
- Molecular Weight 219.24
- Synonym(s) O-methyl-N-(phenylmethyl)-D-Serine methyl ester
- SMILES O=C(O)[C@@H](COC)NC(OC(C)(C)C)=O
Description
(R)-2-((tert-Butoxycarbonyl)amino)-3-methoxypropanoic acid features a chiral center with defined (R)-stereochemistry, enabling precise incorporation into peptide backbones. The tert-butoxycarbonyl group provides stable N-terminal protection, while the methoxy substituent enhances solubility and modulates electronic properties. This derivative supports efficient synthesis of bioactive peptides under standard bench conditions.
Application
(R)-2-((tert-Butoxycarbonyl)amino)-3-methoxypropanoic acid serves as a valuable chiral building block for the synthesis of peptidomimetics and bioactive heterocycles. The protected amine and methoxy-functionalized side chain enable orthogonal reactivity in solid-phase and solution-phase synthesis. Bench-stable and readily purified by chromatography, it facilitates efficient access to complex scaffolds through standard coupling and cyclization protocols.
Synthesis
-
Route1
-
In-stock
3262-72-4 -
77-78-1 - ~99%
-
In-stock
86123-95-7
References
-
SCHWARZ PHARMA AG Patent: WO2006/37574 A1, 2006 ; Location in patent: Page/Page column 17-18 ;
-
-
Route2
-
862372-14-3 - ~99%
-
In-stock
86123-95-7
References
-
ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2005/75439 A1, 2005 ; Location in patent: Page/Page column 127 ; WO 2005/075439 A1
-
-
Route3
-
In-stock
3262-72-4
-
74-88-4
- ~%
-
In-stock
86123-95-7
References
-
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 23 p. 5817 - 5822
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 84.86
- LogP 0.6107
- H_Acceptors 4
- H_Donors 2
- Rotatable_Bonds 4
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 86123-95-7 sigma86123-95-7 manufacturer86123-95-7 price86123-95-7 structure86123-95-7 SDSbuy 86123-95-786123-95-7 supplier86123-95-7 uses86123-95-7 molecular weightprice of 86123-95-786123-95-7 chemical name formula of 86123-95-7