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Structure of 86156-93-6
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3-Fluoro-4-nitrobenzenesulfonyl chloride features a fluorinated aromatic ring paired with electron-withdrawing nitro and sulfonyl chloride groups, enabling selective acylation under mild conditions. This bench-stable reagent facilitates efficient incorporation of sulfonamide moieties into complex molecular architectures, particularly in medicinal chemistry and protein labeling applications.
3-Fluoro-4-nitrobenzenesulfonyl chloride serves as a versatile sulfonylating agent for the selective introduction of sulfonamide groups under mild conditions. Its electron-withdrawing nitro and fluorine substituents enhance reactivity while maintaining bench stability, enabling efficient coupling with amines to afford functionalized sulfonamides. The compound exhibits excellent functional group tolerance and facilitates purification via crystallization or chromatography, making it well-suited for use in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314-H318
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: