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Structure of 6668-56-0
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4-Fluoro-3-nitrobenzenesulfonyl chloride features a strategically positioned fluorine atom and electron-deficient nitro group, enhancing electrophilicity for efficient sulfonylation. This bench-stable reagent enables direct functionalization of nucleophiles in complex molecular architectures under mild conditions.
4-Fluoro-3-nitrobenzenesulfonyl chloride serves as a versatile sulfonylating agent for the selective introduction of sulfonamide groups under mild conditions. Its reactivity is enhanced by the electron-withdrawing nitro and fluorine substituents, enabling efficient coupling with amines and amides. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for use in medicinal chemistry and process development workflows requiring ortho-functionalized sulfonamides.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314-H318
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P405-P501
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Lot numbers can be found on the outside label of a product: