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CS-W001157 4
Total: USD 88.00

3,4,5-Trichlorophenylboronic acid

  • CAS No. 862248-93-9

  • Cat. No. CS-W019927
  • Purity≥98%
  • MDL No.MFCD03095126

*For research and further manufacturing use only, not for direct human use.

3,4,5-Trichlorophenylboronic acid|CS-W019927

Structure of 862248-93-9

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General Information

  • CAS No. 862248-93-9
  • Cat. No. CS-W019927
  • Purity ≥98%
  • MDL No. MFCD03095126
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄BCl₃O₂
  • Molecular Weight 225.26
  • Synonym(s) Boronic acid, B-(3,4,5-trichlorophenyl)-
  • SMILES ClC1=C(Cl)C(Cl)=CC(B(O)O)=C1

Description

3,4,5-Trichlorophenylboronic acid features a highly electron-deficient aryl boronate moiety stabilized by three ortho-chlorine substituents. This bench-stable reagent enables efficient Suzuki-Miyaura couplings under standard conditions, offering enhanced reactivity and predictable regiochemistry in complex molecule synthesis.

Application

3,4,5-Trichlorophenylboronic acid serves as a robust building block in Suzuki-Miyaura cross-coupling reactions, offering high stability and compatibility with diverse functional groups. Its electron-deficient arylboronic acid framework enables efficient coupling with halogenated partners under mild conditions, facilitating the construction of complex biaryl architectures commonly found in pharmaceutical and agrochemical scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   1.3266
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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