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CS-W001157 4
Total: USD 88.00

2-(2,5-Difluorophenyl)ethanol

  • CAS No. 862255-56-9

  • Cat. No. CS-0037438
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(2,5-Difluorophenyl)ethanol|CS-0037438

Structure of 862255-56-9

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General Information

  • CAS No. 862255-56-9
  • Cat. No. CS-0037438
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈F₂O
  • Molecular Weight 158.15
  • Synonym(s) Benzeneethanol, 2,5-difluoro-
  • SMILES C1=C(C=C(CCO)C(=C1)F)F

Description

2-(2,5-Difluorophenyl)ethanol features a fluorinated aromatic ring linked to a primary alcohol via an ethylene tether. This bench-stable compound integrates readily into pharmaceutical intermediates and functional materials, offering enhanced metabolic stability and tunable solubility through its electron-deficient aryl core and polar hydroxyl group.

Application

2-(2,5-Difluorophenyl)ethanol serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles and pharmaceutical intermediates. Its benzylic alcohol functionality facilitates straightforward derivatization—such as oxidation to aldehydes or carboxylic acids—and exhibits good bench stability. The 2,5-difluorophenyl moiety imparts enhanced metabolic stability and modulates electronic properties, making it suitable for optimizing drug-like molecules through targeted functionalization.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   1.4996
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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