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Structure of 863870-88-6
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2-Bromo-3-iodophenol features a dual halogen substitution pattern on the phenolic ring, enabling selective functionalization in cross-coupling reactions. The ortho-halogen arrangement enhances reactivity while maintaining stability under standard handling conditions. This compound serves as a key intermediate in the synthesis of bioactive molecules and specialty materials.
2-Bromo-3-iodophenol serves as a versatile diaryl building block for palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl scaffolds. Its orthogonal halogen reactivity facilitates sequential functionalization, while the phenolic hydroxyl group offers opportunities for derivatization or protection. The compound exhibits good bench stability and is readily purified by crystallization or column chromatography, making it well-suited for iterative synthesis in medicinal chemistry and materials development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: