1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylic acid

Name: 1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 86447-11-2
Cat. No. CS-W018879
Purity≥97%
MDL No.MFCD11519232

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylic acid|CS-W018879

Structure of 86447-11-2

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Description

1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylic acid serves as a stable, bench-ready precursor for functionalized tetrahydropyridine scaffolds. The Boc group enables selective deprotection under mild acidic conditions, while the carboxylic acid moiety facilitates conjugation via amide or ester linkages. This compound integrates readily into synthetic sequences requiring nitrogen-containing heterocycles with controlled reactivity and enhanced solubility in organic media.

Application

1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylic acid serves as a versatile building block for the synthesis of substituted tetrahydropyridine scaffolds prevalent in medicinal chemistry. The Boc group provides excellent stability and orthogonal deprotection compatibility, enabling controlled functionalization at the nitrogen. The carboxylic acid moiety facilitates coupling reactions with amines and alcohols under standard conditions, supporting efficient access to diverse analogs. Its bench-stable nature and predictable reactivity make it ideal for multi-step syntheses and process development.

General Information

CAS No. 86447-11-2
Cat. No. CS-W018879
Purity ≥97%
MDL No. MFCD11519232
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₁₇NO₄
Molecular Weight 227.26
Synonym(s) 1-(tert-butoxycarbonyl)-1,2,5,6-tetrahydropyridine-3-carboxylic acid
SMILES O=C(C1=CCCN(C(OC(C)(C)C)=O)C1)O

Computational Chemistry Data

TPSA 66.84
LogP 1.6382
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

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GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Other Classifications

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Aliphatic heterocycle compounds Other aliphatic heterocycles compounds

Key Words

86447-11-2 sigma86447-11-2 manufacturer86447-11-2 price86447-11-2 structure86447-11-2 SDSbuy 86447-11-286447-11-2 supplier86447-11-2 uses86447-11-2 molecular weightprice of 86447-11-286447-11-2 chemical name formula of 86447-11-2

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1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylic acid

CAS No. 86447-11-2

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