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Structure of 864754-13-2
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tert-Butyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl)piperazine-1-carboxylate features a boronate ester group enabling efficient Suzuki-Miyaura coupling. The piperazine core offers versatile functionalization potential, while the tert-butyl carbamate provides stability and ease of removal under mild acidic conditions. This reagent streamlines access to complex biaryl-piperazine scaffolds in medicinal chemistry.
tert-Butyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl)piperazine-1-carboxylate serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The tetramethylborolane moiety enables reliable coupling with aryl halides under mild conditions, while the piperazine-carboxylate scaffold provides a stable, bench-ready platform for constructing complex pharmaceutical intermediates. Functional group tolerance and ease of purification support its use in iterative synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P341-P312-P330-P363-P501
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Lot numbers can be found on the outside label of a product: