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Structure of 86626-38-2
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4-Bromoindoline is a bench-stable heterocyclic building block featuring a bromine substituent at the 4-position of the indoline core. This electron-deficient moiety enables direct functionalization in cross-coupling reactions and serves as a key intermediate in the synthesis of biologically active compounds, particularly within medicinal chemistry and materials science applications.
4-Bromoindoline serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling direct functionalization at the C4 position. Its bromine substituent facilitates palladium-catalyzed cross-coupling reactions, including Suzuki, Stille, and Negishi couplings, with high efficiency and selectivity. The indoline core provides a rigid, nitrogen-containing scaffold compatible with diverse downstream transformations, including oxidation to indolinones and electrophilic substitution. Bench-stable and readily purified by recrystallization or chromatography, 4-bromoindoline functions as a key intermediate in the construction of bioactive molecules and pharmaceutical candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: